Grant Brown - Colloquium Speaker

Assistant Professor, Department of Biostatistics, University of Iowa
Thursday, October 22, 2020 - 3:15pm
Colloquium Title: 
Modelling the Enzootic Cycle of Borrelia burgdorferi for Planning and Evaluating Interventions


Lyme Disease is the most common vector-borne illness in the U.S. and presents serious public health risks throughout the northern U.S. and Canada. This illness, caused by the bacterial pathogen Borrelia burgdorferi and transmitted primarily by black-legged ticks (Ixodes scapularis), presents unique challenges for infectious disease models, as well as unique opportunities for public health interventions. The pathogen is maintained in the environment thanks to a complex interaction of vector and reservoir animal species, over multiple tick life-stages and seasons. Interventions must therefore seek to interrupt the transmission to incidental hosts (humans and domestic dogs) – a strategy which has primarily focused on prevention of exposure to the tick vector. In this work, we present two related analyses. First, we explore new evidence for the mechanisms by which transfer of the infectious agent can be interrupted in mouse populations. Second, we apply these findings to develop an improved Bayesian ecological model of data from a prior reservoir vaccination study. Finally, we’ll explore the implications for interventions, and describe ongoing efforts to better understand the impact of these processes on human health.


Everyone is welcome to join! Please note that the meeting opens at 3:15pm, and the presentation is at 3:30-4:20pm. There will be time afterward for Q&A with the speaker.

Topic: Colloquia: Department of Statistics and Actuarial Science, The University of Iowa

Time: Oct 22, 2020 03:15 PM Central Time (US and Canada)

Join Zoom Meeting

Meeting ID: 970 2130 9544

One tap mobile

+13126266799,,97021309544# US (Chicago)

+16468769923,,97021309544# US (New York)

Dial by your location

        +1 312 626 6799 US (Chicago)

        +1 646 876 9923 US (New York)

        +1 301 715 8592 US (Germantown)

        +1 346 248 7799 US (Houston)

        +1 669 900 6833 US (San Jose)

        +1 253 215 8782 US (Tacoma)

Meeting ID: 970 2130 9544

Find your local number:

Join by SIP

Join by H.323 (US West) (US East) (India Mumbai) (India Hyderabad) (Amsterdam Netherlands) (Germany) (Australia) (Brazil) (Canada) (Japan)

Meeting ID: 970 2130 9544